Neuropilin 1-Sema Signaling Regulates Crossing of Cingulate Pioneering Axons during Development of the Corpus Callosum
نویسندگان
چکیده
منابع مشابه
Neuropilin 1-Sema signaling regulates crossing of cingulate pioneering axons during development of the corpus callosum.
Pioneer axons from the cingulate cortex initiate corpus callosum (CC) development, yet nothing is known about the molecules that regulate their guidance. We demonstrate that neuropilin 1 (Npn1) plays an integral role in the development of the CC. Npn1 is localized to axons of cingulate neurons as they cross the midline, and multiple class 3 semaphorins (Semas) are expressed around the developin...
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ژورنال
عنوان ژورنال: Cerebral Cortex
سال: 2009
ISSN: 1460-2199,1047-3211
DOI: 10.1093/cercor/bhp027